The Center offers patients with diabetes the opportunity
to participate in clinical trials of new treatments for diabetes.
The following clinical trials are recruiting children and/or
adolescents with diabetes.


Type 1 Diabetes Natural History Study

Principal Investigator
Dr. Robin Goland

Purpose of Study
To determine risk of development of type 1 diabetes in relatives of people with type 1 diabetes.  Subjects have a simple blood test to measure antibodies against islet cells.  About 96% of relatives of someone with type 1 diabetes will have no measurable antibodies and therefore a low risk of subsequent development of type 1 diabetes.  The 4% of relatives who test positive for islet antibodies will be eligible for confirmatory testing and for consideration of future trials aimed at preventing type 1 diabetes.

Who is Eligible for the Study?
Age:  Between 1 and 45 years old

Type of Diabetes:  Type 1 diabetes

Ideal Candidate:  Siblings, mothers, fathers, cousins of people with type 1 diabetes

Exclusion criteria:  Subjects older than 45

Time Commitment:  Visit for blood test, about 15 minutes.  Subjects with positive antibody tests are invited to participate in further studies.

Adolescent-Onset Type 2 Diabetes Family Study

Principal Investigators
Drs. Rudolph Leibel, Michael Rosenbaum, Robin Goland

Purpose of Study
To identify the genes responsible for early-onset type 2 diabetes by studying parents and siblings of people with type 2 diabetes that was diagnosed prior to age 25.  Subjects undergo a history, physical exam and lab tests including a rapid intravenous glucose tolerance test.

Ideal Candidate:  Siblings, mothers, fathers of people with type 2 diabetes diagnosed prior to age 25

Exclusion Criteria:  Subjects younger than 8 yrs old

Time Commitment:  1 visit for history, exam and blood tests including a glucose tolerance test, about 1-2 hours.